简体中文 English

Leading Experts in DMPK, Pharmacology, and Safety services for Innovative Drug Development

Services
DMPK Services

In Vivo Pharmacokinetics
Pharmacokinetics (PK) describes how the body affects the absorption, distribution, metabolism, and excretion (ADME) processes of specific xenobiotics/chemicals or their metabolites after administration. Early in vivo PK profiling provide a basis for choosing new molecular entities (NMEs) and lead compounds. It is necessary for drug candidate selection (CS) and late‐stage preclinical and clinical development.

In Vitro ADME Services
In vitro ADME services can effectively provide evaluations of compounds’ absorption, distribution, metabolism, and drug interactions. These services aid in understanding the behavior of compounds within the human body, providing a critical basis for dosage setting, side effect predicting, and risk assessment during the development process.


MetID (Metabolite Profiling and Identification)

Understanding the metabolic pathway and the structure of the metabolites is important for the design and optimization of lead compounds, safety assessment in drug development, and support of IND and/or NDA filings. MetID studies help understand the clearance pathways, find active/reactive metabolites, and discover human disproportionate/unique metabolites to support the evaluation of drug efficacy and safety.

Bioanalysis has become an indispensable part of new drug research. Bioanalysis can accurately determine the concentrations of target analytes in biological matrices, providing data support for drug safety and efficacy.
Bioanalysis

Pharmacology, and Safety Services

Pharmacodynamics Services

Pharmacodynamics (PD) plays a pivotal role in understanding the intricate mechanisms through which drugs exert their effects on the human body.


By bridging biochemistry and physiology, PD investigates the dynamic relationship between drug concentration and its therapeutic or adverse outcomes…

Safety Assessment Services

we partner with pharmaceutical and biotech companies to streamline the path from discovery to IND submission through our comprehensive GLP and non-GLP toxicology services. With GLP-certified, AAALAC-accredited facilities, a team of seasoned scientists, and advanced technologies, we deliver high-quality safety assessment…